Adenocarcinoma of vagina

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Vaginal Cancer

Vaginal Cancer | MD Anderson Cancer Center

We present a case of a year-old woman with a long-standing history of persistent cervical dysplasia that resulted in a hysterectomy. Over the course of 2 years, the patient underwent 2 CO 2 laser vaporization procedures of the upper vagina and intermittent 5-fluorouracil therapy. A biopsy performed at the time of the second laser procedure revealed endocervical-type well-differentiated adenocarcinoma, associated with VAIN III. HPV in situ hybridization for HPV types 16 and 18 was positive in both the glandular and squamous mucosa. The patient has no known history of intrauterine diethylstilbestrol exposure or mullerian developmental abnormalities. Subsequently, the patient underwent a radical upper vaginetcomy with bilateral pelvic lymph nodes dissection and bilateral salpingo-oophorectomy. The vaginectomy specimen showed residual adenocarcinoma associated with VAIN-III and extensive vaginal adenosis with free resection margins.
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Cancer of the vagina (vaginal cancer)

Here we present a rare case of primary mucinous adenocarcinoma of vagina treated successfully with wide local excision and post-operative radiotherapy. There was no recurrence even after four years. Advanced Search.
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A neoplasm is another name for cancer. Cancer is a disease characterized by the uncontrollable multiplication of abnormal cells. It can occur in many parts of the body, including the vagina.
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